PRF + Microneedling
Pre & Post Care Guide

What to Expect

PRF + Microneedling is a powerful combination treatment that uses your body's own platelet-rich fibrin alongside controlled micro-channels to stimulate deep collagen production and accelerate skin renewal. Here is what a typical treatment experience looks like:

• A small amount of blood is drawn from your arm (similar to a routine blood test) and spun in a centrifuge to isolate your PRF.

• A topical numbing cream is applied to your face for 30–45 minutes before treatment begins.

• The microneedling device creates thousands of tiny micro-channels across the treatment area.

• Your PRF is applied directly to the skin and massaged in, allowing the growth factors to penetrate deeply.

• The full appointment typically takes 60–90 minutes.

• Mild redness, warmth, and swelling are normal immediately after treatment.

Pre-Treatment Instructions

Preparing your skin properly before your appointment is essential for safety and optimal results.

7 Days Before

• Discontinue use of retinol, tretinoin, retinoids, and all vitamin A derivatives.

• Avoid exfoliating acids (AHAs, BHAs, glycolic acid, salicylic acid, lactic acid).

• Do not use any harsh or abrasive scrubs on the treatment area.

• Avoid waxing, threading, laser treatments, or chemical peels.

• Inform your provider of any medications, supplements, or medical conditions.

• Avoid blood-thinning medications and supplements if medically safe to do so (aspirin, ibuprofen, fish oil, vitamin E, turmeric). Consult your doctor before stopping any prescribed medications.

• Avoid alcohol consumption — it can thin the blood and affect PRF quality.

• Stay well hydrated. Drink plenty of water in the days leading up to your appointment.

• Avoid excessive sun exposure and do not come in with an active sunburn.

• Do not use self-tanner or spray tan on the treatment area.

• Arrive with a clean face — no makeup, moisturizer, sunscreen, or skincare products.

• Eat a light meal and drink water before your appointment. Do not come in fasted.

• Avoid caffeine on the morning of your appointment if possible.

• Wear comfortable, loose clothing. Avoid tight collars or anything that may rub the face.

• Let your provider know of any new medications, illnesses, or skin changes since your last visit.

Post-Treatment Instructions

The 72 hours following your treatment are critical. Your skin is in active repair mode — treat it gently and follow these guidelines closely.

First 24 Hours

• Do NOT wash your face for at least 6–8 hours after treatment.

• Do not apply any skincare products, makeup, or sunscreen for the first 24 hours.

• Avoid touching, rubbing, or picking at the treated area.

• Sleep on a clean pillowcase and try to sleep on your back to avoid friction.

• Avoid sweating — no exercise, hot showers, saunas, or steam rooms.

• Avoid direct sun exposure. If you must go outside, wear a wide-brimmed hat.

• Do not apply ice or cold compresses directly to the skin.

• Gently cleanse with a mild, fragrance-free cleanser using your fingertips only — no washcloths or brushes.

• Apply a gentle, fragrance-free moisturizer to keep skin hydrated.

• Continue to avoid all active ingredients: retinol, acids, vitamin C, benzoyl peroxide.

• Avoid makeup if possible. If necessary, use only mineral-based products.

• Continue to avoid sun exposure and strenuous exercise.

• Some peeling, flaking, or tightness is normal — do not pick or peel the skin.

• You may gradually reintroduce your regular skincare routine as tolerated.

• Begin applying SPF 30+ sunscreen daily — sun protection is essential during healing.

• Avoid retinoids and strong exfoliants for at least 7–10 days post-treatment.

• Stay hydrated and maintain a gentle skincare routine.

• Contact your provider if you experience unusual pain, prolonged redness, or signs of infection.

What to Avoid After Treatment

• Retinol, tretinoin, and all retinoids — wait at least 7–10 days

• Exfoliating acids (AHAs, BHAs, glycolic, salicylic) — wait at least 7 days

• Vitamin C serums — wait at least 5–7 days

• Benzoyl peroxide or acne treatments — wait at least 7 days

• Waxing, threading, or hair removal on treated area — wait at least 2 weeks

• Chemical peels or laser treatments — wait at least 4 weeks

• Prolonged sun exposure without SPF — ongoing

• Tanning beds — avoid completely during healing

• Swimming pools, hot tubs, or open water — wait at least 72 hours

• Alcohol consumption — wait at least 24–48 hours

Frequently Asked Questions